Laser-assisted cell direct-write technique has been a promising biomaterial direct-write method. For safe and reproducible cell direct writing, cell injury due to process-induced external stress must be understood in addition to biological property research. The objective of this study is to model the thermoelastic stress wave propagation inside the coating in laser-assisted cell direct writing when vaporization and/or optical breakdown of coating materials is/are not available. It is found that a bipolar pressure pair, with peak magnitudes on the order of 1 MPa or higher, has been developed within a finite thin coating medium. Shorter duration laser pulses lead to higher thermoelastic stresses. This study will help to understand the photomechanical stress and its relevance with biomaterial damage in laser-assisted cell direct writing.

1.
Barron
,
J. A.
,
Wu
,
P.
,
Ladouceur
,
H. D.
, and
Ringeisen
,
B. R.
, 2004, “
Biological Laser Printing: A Novel Technique for Creating Heterogeneous 3-Dimensional Cell Patterns
,”
Biomed. Microdevices
1387-2176,
6
(
2
), pp.
139
147
.
2.
Lin
,
Y.
,
Huang
,
Y.
,
Wang
,
G.
,
Tzeng
,
T. J.
, and
Chrisey
,
D. B.
, 2009, “
Effect of Laser Fluence on Yeast Cell Viability in Laser-Assisted Cell Transfer
,”
J. Appl. Phys.
0021-8979,
106
(
4
), p.
043106
.
3.
Odde
,
D. J.
, and
Renn
,
M. J.
, 1999, “
Laser-Guided Direct Writing for Applications in Biotechnology
,”
Trends Biotechnol.
0167-7799,
17
(
10
), pp.
385
389
.
4.
Odde
,
D. J.
, and
Renn
,
M. J.
, 2000, “
Laser-Guided Direct Writing of Living Cells
,”
Biotechnol. Bioeng.
0006-3592,
67
(
3
), pp.
312
318
.
5.
Sigrist
,
M. W.
, and
Kneubühl
,
F. K.
, 1978, “
Laser-Generated Stress Waves in Liquids
,”
J. Acoust. Soc. Am.
0001-4966,
64
(
6
), pp.
1652
1663
.
6.
Park
,
H. K.
,
Kim
,
D.
,
Grigoropoulos
,
C. P.
, and
Tam
,
A. C.
, 1996, “
Pressure Generation and Measurement in the Rapid Vaporization of Water on a Pulsed-Laser-Heated Surface
,”
J. Appl. Phys.
0021-8979,
80
(
7
), pp.
4072
4081
.
7.
Wang
,
W.
,
Li
,
G.
, and
Huang
,
Y.
, 2009, “
Modeling of Bubble Expansion-Induced Cell Mechanical Profile in Laser-Assisted Cell Direct Writing
,”
ASME J. Manuf. Sci. Eng.
1087-1357,
131
(
5
), p.
051013
.
8.
Paltauf
,
G.
, and
Schmidt-Kloiber
,
H.
, 1998, “
Photoacoustic Waves Excited in Liquids by Fiber-Transmitted Laser Pulses
,”
J. Acoust. Soc. Am.
0001-4966,
104
(
2
), pp.
890
897
.
9.
Georgiou
,
S.
, and
Koubenakis
,
A.
, 2003, “
Laser-Induced Material Ejection From Model Molecular Solids and Liquids: Mechanisms, Implications, and Applications
,”
Chem. Rev. (Washington, D.C.)
0009-2665,
103
(
2
), pp.
349
394
.
10.
Park
,
H. K.
, 1994, “
Heat and Momentum Transfer on the Rapid Phase Change of Liquid Induced by Nanosecond-Pulsed Laser Irradiation
,” Ph.D. thesis, University of California, Berkeley, CA.
11.
Paltauf
,
G.
, and
Schmidt-Kloiber
,
H.
, 1997, “
Measurement of Laser-Induced Acoustic Waves With a Calibrated Optical Transducer
,”
J. Appl. Phys.
0021-8979,
82
(
4
), pp.
1525
1531
.
12.
Vogel
,
A.
, and
Venugopalan
,
V.
, 2003, “
Mechanisms of Pulsed Laser Ablation of Biological Tissues
,”
Chem. Rev. (Washington, D.C.)
0009-2665,
103
(
2
), pp.
577
644
.
13.
Dingus
,
R. S.
, and
Scammon
,
R. J.
, 1991, “
Grüneisen-Stress Induced Ablation of Biological Tissue
,”
Proc. SPIE
0277-786X,
1427
, pp.
45
54
.
14.
Dingus
,
R. S.
,
Curran
,
D. R.
,
Oraevsky
,
A. A.
, and
Jacques
,
S. L.
, 1994, “
Microscopic Spallation Process and Its Potential Role in Laser-Tissue Ablation
,”
Proc. SPIE
0277-786X,
2134A
, pp.
434
445
.
15.
Carome
,
E. F.
,
Clark
,
N. A.
, and
Moeller
,
C. E.
, 1964, “
Generation of Acoustic Signals in Liquids by Ruby Laser-Induced Thermal Stress Transients
,”
Appl. Phys. Lett.
0003-6951,
4
, pp.
95
97
.
16.
Frenz
,
M.
,
Paltauf
,
G.
, and
Schmidt-Kloiber
,
H.
, 1996, “
Laser-Generated Cavitation in Absorbing Liquid Induced by Acoustic Diffraction
,”
Phys. Rev. Lett.
0031-9007,
76
(
19
), pp.
3546
3549
.
17.
Paltauf
,
G.
, and
Dyer
,
P. E.
, 2003, “
Photomechanical Process and Effects in Ablation
,”
Chem. Rev. (Washington, D.C.)
0009-2665,
103
(
2
), pp.
487
518
.
18.
Anderson
,
R. R.
, and
Parrish
,
J. A.
, 1983, “
Selective Photothermolysis: Precise Microsurgery by Selective Absorption of Pulsed Radiation
,”
Science
0036-8075,
220
, pp.
524
527
.
19.
Gusev
,
V. E.
, and
Karabutov
,
A. A.
, 1993,
Laser Optoacoustics
,
American Institute of Physics
,
New York
.
20.
Noack
,
J.
, and
Vogel
,
A.
, 1999, “
Laser-Induced Plasma Formation in Water at Nanosecond to Femtosecond Time Scales: Calculation of Thresholds, Absorption Coefficients, and Energy Density
,”
IEEE J. Quantum Electron.
0018-9197,
35
(
8
), pp.
1156
1167
.
21.
Kim
,
D.
,
Ye
,
M.
, and
Grigoropoulos
,
C. P.
, 1998, “
Pulsed Laser-Induced Ablation of Absorbing Liquids and Acoustic-Transient Generation
,”
Appl. Phys. A: Mater. Sci. Process.
0947-8396,
67
, pp.
169
181
.
You do not currently have access to this content.