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Journal Articles

A Quantitative Study of Transport of Surfactant Boli in a Three-Dimensional Lung Model of Neonates

Hannah Combs, Taylor Shark, Jacob Heiss, Mehdi Raessi, Hossein Tavana
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021006.
Paper No: BIO-22-1119
DOI: https://doi.org/10.1115/1.4055428
Published Online: October 6, 2022
View Article titled, A Quantitative Study of Transport of Surfactant Boli in a Three-Dimensional Lung Model of Neonates
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Topics: Lung, Surfactants
Includes: Supplementary data
Journal Articles

Estimation of Regional Pulmonary Compliance in Idiopathic Pulmonary Fibrosis Based on Personalized Lung Poromechanical Modeling

Cécile Patte, Pierre-Yves Brillet, Catalin Fetita, Jean-François Bernaudin, Thomas Gille, Hilario Nunes, Dominique Chapelle, Martin Genet
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. September 2022, 144(9): 091008.
Paper No: BIO-21-1444
DOI: https://doi.org/10.1115/1.4054106
Published Online: March 30, 2022
View Article titled, Estimation of Regional Pulmonary Compliance in Idiopathic Pulmonary Fibrosis Based on Personalized Lung Poromechanical Modeling
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Topics: Displacement, Lung, Diseases, Pressure, Porosity, Modeling
Journal Articles

Evaluating the Limits in the Biomechanics of Blunt Lung Injury

Madelyn A. K. Eaton, Justin A. McMahon, Robert S. Salzar
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. September 2022, 144(9): 090801.
Paper No: BIO-21-1345
DOI: https://doi.org/10.1115/1.4054057
Published Online: March 30, 2022
View Article titled, Evaluating the Limits in the Biomechanics of Blunt Lung Injury
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Topics: Lung, Wounds, Biological tissues, Testing, Modeling, Mechanical testing, Biomechanics, Injury mechanisms
Journal Articles

Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice

Abhay B. Ramachandra, Nicole Mikush, Maor Sauler, Jay D. Humphrey, Edward P. Manning
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081008.
Paper No: BIO-21-1330
DOI: https://doi.org/10.1115/1.4053873
Published Online: March 11, 2022
View Article titled, Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice
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Topics: Fibers, Lung, Pressure, Pulmonary artery, Stress, Ventilation, Energy storage, Stiffness, Diseases, Vessels
Includes: Supplementary data
Journal Articles

Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study

Rachelle Walter, Kendall Hunter, Kurt Stenmark, Vitaly O. Kheyfets
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. February 2022, 144(2): 024503.
Paper No: BIO-20-1512
DOI: https://doi.org/10.1115/1.4051719
Published Online: September 30, 2021
View Article titled, Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study
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Topics: Engineering simulation, Hemodynamics, Modeling, Pressure, Shear stress, Simulation, Stress, Vessels, Lung, Flow (Dynamics)
Journal Articles

Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction

Caymen Novak, Megan N. Ballinger, Samir Ghadiali
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. November 2021, 143(11): 110801.
Paper No: BIO-20-1555
DOI: https://doi.org/10.1115/1.4051118
Published Online: July 14, 2021
View Article titled, Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction
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Topics: Diseases, Lung
Journal Articles

Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study

Adithya Gurumurthy, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2021, 143(11): 111001.
Paper No: BIO-21-1035
DOI: https://doi.org/10.1115/1.4051217
Published Online: July 14, 2021
View Article titled, Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study
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Topics: Aerosols, Drugs, Flow (Dynamics), Nanoparticles, Particulate matter, Lung, Diffusion (Physics), Fluids, Drug delivery systems
Journal Articles

Effects of Pulmonary Fibrosis and Surface Tension on Alveolar Sac Mechanics in Diffuse Alveolar Damage

Long Chen, Weiwei Tao, Wei Ji, Yan Lu, Xia Zhao
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2021, 143(8): 081013.
Paper No: BIO-20-1519
DOI: https://doi.org/10.1115/1.4050789
Published Online: May 6, 2021
View Article titled, Effects of Pulmonary Fibrosis and Surface Tension on Alveolar Sac Mechanics in Diffuse Alveolar Damage
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Topics: Biological tissues, Damage, Fluid structure interaction, Lung, Surface tension, Flow (Dynamics), Surfactants, Air flow, Pressure
Journal Articles

Assessment of Thorax Finite Element Model Response for Behind Armor Blunt Trauma Impact Loading Using an Epidemiological Database

D. S. Cronin, M. C. Bustamante, J. Barker, D. Singh, K. A. Rafaels, C. Bir
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031007.
Paper No: BIO-20-1185
DOI: https://doi.org/10.1115/1.4048644
Published Online: December 10, 2020
View Article titled, Assessment of Thorax Finite Element Model Response for Behind Armor Blunt Trauma Impact Loading Using an Epidemiological Database
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Topics: Armor, Wounds, Projectiles, Fracture (Materials), Fracture (Process), Databases, Deformation, Lung, Finite element model
Journal Articles

Effect of Non-Newtonian Dynamics on the Clearance of Mucus From Bifurcating Lung Airway Models

Rahul R. Rajendran, Arindam Banerjee
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. February 2021, 143(2): 021011.
Paper No: BIO-20-1186
DOI: https://doi.org/10.1115/1.4048474
Published Online: November 11, 2020
View Article titled, Effect of Non-Newtonian Dynamics on the Clearance of Mucus From Bifurcating Lung Airway Models
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Topics: Air flow, Bifurcation, Clearances (Engineering), Flow (Dynamics), Geometry, Shear (Mechanics), Lung, Trachea, Gravity (Force), Viscosity
Journal Articles

In Vivo Characterization of the Swine Airway Morphometry and Motion Based on Computed Tomographic Imaging During Respiration

Meryll Grace B. Castro, Nicole A. Varble, Rex C. Yung, Bradford J. Wood, John W. Karanian, William F. Pritchard
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. December 2020, 142(12): 121009.
Paper No: BIO-20-1040
DOI: https://doi.org/10.1115/1.4047550
Published Online: September 8, 2020
View Article titled, In Vivo Characterization of the Swine Airway Morphometry and Motion Based on Computed Tomographic Imaging During Respiration
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Topics: Bifurcation, Deformation, Imaging, Lung, Image segmentation, Dynamics (Mechanics)
Journal Articles

A Microfluidic System to Measure Neonatal Lung Compliance Over Late Stage Development as a Functional Measure of Lung Tissue Mechanics

Laurel E. Schappell, Daniel J. Minahan, Jason P. Gleghorn
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. October 2020, 142(10): 100803.
Paper No: BIO-19-1556
DOI: https://doi.org/10.1115/1.4047133
Published Online: August 31, 2020
View Article titled, A Microfluidic System to Measure Neonatal Lung Compliance Over Late Stage Development as a Functional Measure of Lung Tissue Mechanics
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Topics: Lung, Biological tissues, Microfluidics, Pressure, Calibration
Journal Articles

Dynamics of the Tracheal Airway and Its Influences on Respiratory Airflows: An Exemplar Study

Bora Sul, Talissa Altes, Kai Ruppert, Kun Qing, Daniel S. Hariprasad, Michael Morris, Jaques Reifman, Anders Wallqvist
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2019, 141(11): 111009.
Paper No: BIO-19-1044
DOI: https://doi.org/10.1115/1.4043723
Published Online: July 31, 2019
View Article titled, Dynamics of the Tracheal Airway and Its Influences on Respiratory Airflows: An Exemplar Study
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Topics: Air flow, Flow (Dynamics), Trachea, Deformation, Dynamics (Mechanics), Lung
Includes: Supplementary data
Journal Articles

Do Pulmonary Cavity Shapes Influence Lung Function?

H. Minaeizaeim, H. Kumar, M. H. Tawhai, C. King, E. A. Hoffman, M. Wilsher, D. Milne, A. R. Clark
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2019, 141(11): 111005.
Paper No: BIO-18-1356
DOI: https://doi.org/10.1115/1.4044092
Published Online: July 30, 2019
View Article titled, Do Pulmonary Cavity Shapes Influence Lung Function?
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Topics: Biological tissues, Lung, Shapes, Cavities, Density
Journal Articles

Special Issue: A Tribute to Dr. Y. C. Fung

Hai-Chao Han, Shu Qian Liu, X. Edward Guo
Journal: Journal of Biomechanical Engineering
Article Type: Guest Editorial
J Biomech Eng. September 2019, 141(9): 090301.
Paper No: BIO-19-1311
DOI: https://doi.org/10.1115/1.4044065
Published Online: July 10, 2019
View Article titled, Special Issue: A Tribute to Dr. Y. C. Fung
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Topics: Bioengineering, Biomechanical engineering, Biomechanics, Biomedicine, Students, Biological tissues, Engineering teachers, Biomedical engineering, Biotransport, Blood
Journal Articles

Engineered Airway Models to Study Liquid Plug Splitting at Bifurcations: Effects of Orientation and Airway Size

Antonio Copploe, Morteza Vatani, Rouzbeh Amini, Jae-Won Choi, Hossein Tavana
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. September 2018, 140(9): 091012.
Paper No: BIO-17-1548
DOI: https://doi.org/10.1115/1.4040456
Published Online: June 26, 2018
View Article titled, Engineered Airway Models to Study Liquid Plug Splitting at Bifurcations: Effects of Orientation and Airway Size
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Topics: Bifurcation, Fluids, Surfactants, Dynamics (Mechanics), Design, Lung, Gravity (Force)
Includes: Supplementary data
Journal Articles

Simulation of Airflow in an Idealized Emphysematous Human Acinus

Amitvikram Dutta, Dragos M. Vasilescu, James C. Hogg, A. B. Phillion, J. R. Brinkerhoff
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. July 2018, 140(7): 071001.
Paper No: BIO-17-1253
DOI: https://doi.org/10.1115/1.4039680
Published Online: April 19, 2018
View Article titled, Simulation of Airflow in an Idealized Emphysematous Human Acinus
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Topics: Air flow, Ducts, Flow (Dynamics), Oxygen, Simulation, Lung
Journal Articles

Modeling Inspiratory Flow in a Porcine Lung Airway

Peshala P. T. Gamage, Fardin Khalili, M. D. Khurshidul Azad, Hansen A Mansy
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. June 2018, 140(6): 061003.
Paper No: BIO-17-1336
DOI: https://doi.org/10.1115/1.4038431
Published Online: March 19, 2018
View Article titled, Modeling Inspiratory Flow in a Porcine Lung Airway
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Topics: Flow (Dynamics), Lung, Pressure drop, Bifurcation, Trachea, Turbulence, Boundary-value problems
Journal Articles

Assessing Airflow Sensitivity to Healthy and Diseased Lung Conditions in a Computational Fluid Dynamics Model Validated In Vitro

Bora Sul, Zachary Oppito, Shehan Jayasekera, Brian Vanger, Amy Zeller, Michael Morris, Kai Ruppert, Talissa Altes, Vineet Rakesh, Steven Day, Risa Robinson, Jaques Reifman, Anders Wallqvist
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2018, 140(5): 051009.
Paper No: BIO-16-1533
DOI: https://doi.org/10.1115/1.4038896
Published Online: March 12, 2018
View Article titled, Assessing Airflow Sensitivity to Healthy and Diseased Lung Conditions in a Computational Fluid Dynamics Model Validated In Vitro
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Topics: Air flow, Flow (Dynamics), Lung, Geometry
Journal Articles

Simulation of Forced Expiration in a Biophysical Model, With Homogeneous and Clustered Bronchoconstriction

Kerry L. Hedges, Merryn H. Tawhai
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. June 2016, 138(6): 061008.
Paper No: BIO-15-1404
DOI: https://doi.org/10.1115/1.4033475
Published Online: May 9, 2016
View Article titled, Simulation of Forced Expiration in a Biophysical Model, With Homogeneous and Clustered Bronchoconstriction
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Topics: Flow (Dynamics), Imaging, Lung, Pressure, Simulation, Biological tissues