To understand brain injuries better, the mechanical properties of brain tissue have been studied for ; however, no universally accepted data set exists. The variation in material properties reported may be caused by differences in testing methods and protocols used. An overview of studies on the mechanical properties of brain tissue is given, focusing on testing methods. Moreover, the influence of important test conditions, such as temperature, anisotropy, and precompression was experimentally determined for shear deformation. The results measured at room temperature show a stiffer response than those measured at body temperature. By applying the time-temperature superposition, a horizontal shift factor was found, which is in agreement with the values found in literature. Anisotropy of samples from the corona radiata was investigated by measuring the shear resistance for different directions in the sagittal, the coronal, and the transverse plane. The results measured in the coronal and the transverse plane were 1.3 and 1.25 times stiffer than the results obtained from the sagittal plane. The variation caused by anisotropy within the same plane of individual samples was found to range from 25% to 54%. The effect of precompression on shear results was investigated and was found to stiffen the sample response. Combinations of these and other factors (postmortem time, donor age, donor type, etc.) lead to large differences among different studies, depending on the different test conditions.
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June 2008
Research Papers
The Influence of Test Conditions on Characterization of the Mechanical Properties of Brain Tissue
M. Hrapko,
M. Hrapko
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
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J. A. W. van Dommelen,
J. A. W. van Dommelen
Materials Technology Institute,
e-mail: j.a.w.v.dommelen@tue.nl
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
G. W. M. Peters,
G. W. M. Peters
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
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J. S. H. M. Wismans
J. S. H. M. Wismans
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
Search for other works by this author on:
M. Hrapko
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
J. A. W. van Dommelen
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlandse-mail: j.a.w.v.dommelen@tue.nl
G. W. M. Peters
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
J. S. H. M. Wismans
Materials Technology Institute,
Eindhoven University of Technology
, P.O. Box 513, 5600 MB Eindhoven, The NetherlandsJ Biomech Eng. Jun 2008, 130(3): 031003 (10 pages)
Published Online: April 22, 2008
Article history
Received:
March 14, 2007
Revised:
September 7, 2007
Published:
April 22, 2008
Citation
Hrapko, M., van Dommelen, J. A. W., Peters, G. W. M., and Wismans, J. S. H. M. (April 22, 2008). "The Influence of Test Conditions on Characterization of the Mechanical Properties of Brain Tissue." ASME. J Biomech Eng. June 2008; 130(3): 031003. https://doi.org/10.1115/1.2907746
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