This study is aimed at reviewing the various literature on the robot-based rehabilitation and the associated technical issues, augmentation, utilization, and safeties. During recent years, Biorobotics and Collaborative Robots have played a remarkable role to provide fast, accurate and efficient therapy and assistance. Most of these robots are equipped with various types of devices to control the intensity, duration, and precision of the training while some feedback systems have also been used to monitor the efficiency of the process and help physicians and therapists to furnish a high quality treatment. Haptic devices, Electromyography (EMG)/Electroencephalography (EEG) sensors, virtual environment and other interactive approaches have been utilized to optimize the process and to investigate different mental as well as physiological aspects. This review paper provides a comprehensive background on the human robot interactions and their outcomes in medical settings and potential research areas in the domain.